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Maria-Grazia DE SIMONI

Maria-Grazia DE SIMONI

Head of the Laboratory of Inflammation and Nervous System Disease
IRCCS-Istituto di Ricerche Farmacologiche Mario Negri


Maria Grazia De Simoni, Doctoral Degree in Biological Sciences in 1977, University of Milano, Italy, 110/110 summa cum laude. 1981: PhD in Neuropharmacology. 1981-1982: European Community fellowship for "Advanced Professional Training", INSERM U 171, Universitè Claude Bernard, Lyon, France. Presently: Head of the Laboratory of Inflammation and Nervous System Diseases, Mario Negri Institute Milan, Italy. She developed a long lasting expertise in experimental models of CNS diseases.Author of more than 110 scientific papers on peer-reviewed international journals.

Research Interest

The main scientific interests presently include the pathogenesis of cerebral ischemia/reperfusion and of traumatic brain injury; the inflammatory response as target of therapeutic strategies; peripheral inflammatory markers in CNS diseases; the protective mechanisms of stem cells. Member of the Scientific Board of Associazione Italiana per la Ricerca sull’Invecchiamento Cerebrale (AIRIC) and of the Editorial Board of Stroke, a Journal of Cerebral Circulation.